Here are some illustrations I've created completely digitally using only a wacom tablet, a MacBook, and Adobe Photoshop.
As with any medium, I am learning that there are certain advantages and disadvantages when creating images completely digitally. One advantage is that editing the image is so much easier. You can modify the artwork without leaving a trace. A big disadvantage, however, is that there is no physical artwork, only ones and zeros, and if you end up deleting or losing your image for any reason, you also leave no trace...